Positive Antinuclear Antibody

A rather odd question, I suppose ... but I was wondering if anyone would know if the ANA blood results with a range of 160 or more could be a sign of infectious mononucleosis (glandular fever)?

Both my cousin and me and my mother and sister, has said several times in the past, some tests we have showed signs of having been in contact with infectious mononucleosis before, but this everything we said. There were no tests done to prove GF centered or not yay at this point.

Anyway, my cousin and I got to talk today about our ANA results (mine is 160, hers are much higher), and she questioned whether it could be fever glandular or not.

Can we be able to answer that question for us?


Cheers, and Thanks for all the help:)

Hello, the ANA test rarely contributes to establish a diagnosis. You probably already know, but I'll mention a few words about the ANA.

Antinuclear antibodies are just that. They are antibodies directed against the nucleus. However, these antibodies may be a problem if they are directed against the bodies own cells.

The thing about antinuclear antibodies is that they represent a type of antibodies that attack the cell nucleus. In other words, the ANA does not test a specific antibody.

Thus, if an antibody binds to the nucleus of a specific model, and the antibody binds to the B nuclear weapon in a different pattern, they will both return a result (+).

The return of a result (+) ANA in itself is not useful because there is a whole series of diseases that can produce a lupus (+) of ANA, including joint pain arthritis, scleroderma Some types of thyroid disease, certain types of liver / gallbladder disease, and even infectious mononucleosis.

In addition, a (+) ANA can be seen in normal individuals, and therefore, these results can be called as a "false positive. The number 160 that you give refers to the amount they have to dilute the product to always get a false positive result.

A false (+) result is likely when the title is less than 1:80. A false (+) result is unlikely if the security is greater than 1:320. Thus, the value of your lies in a range of indefinite duration.

Now, with regard to Mono, to be honest, I've never used an ANA to confirm or exclude infectious mononucleosis. If there is suspicion of another autoimmune disease, I can order it, but for Mono, I would not order an ANA.

To diagnose Mono, the clinical syndrome is the most important "test". The patient must have a fever, sore throat and lymph nodes in his neck. A confirmation test then include consideration of the patient's blood on a slide to look for specific morphological characteristics of the patient's white blood cells.

Another confirmatory test is the "Monospot" test. Another name for this is the antibody test hetophile. When a patient develops infectious mononucleosis, he / she will produce antibodies to fight infection. It was found Some of these antibodies bind to independent agents. In the case of the test Monospot, these agents are cells of sheep blood cells of horse blood, beef and even goat's blood cells.

So, to answer your question, a (+) ANA can somehow be associated with mono, but it's really like saying "this is the fact that you're driving a nice car sign you went to a good college? "

They are loosely linked, but the ANA is nonspecific, may be linked to a number of other diseases, and may even be normal. Finally, there are better ways to build Mono. There are even tests to detect the virus itself (Epstein Barr).

Hope I have answered your question with my lengthy ramblings!

I do not know if there is a link Betwa.